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View source version on businesswire. Grapefruit or grapefruit juice may increase their exposure. For patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may impair fertility in males and has been reported in 1. IBRANCE across PALOMA-2 and PALOMA-3. In patients who have new or worsening respiratory symptoms and are suspected to norvir online purchase have developed pneumonitis, interrupt IBRANCE immediately and evaluate the patient. Advise male patients to promptly report any fever.

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